Bio-identical Hormone Replacement Therapy - North Tampa, Florida

Why Hormone replacement?

For years Doctors have been treating men and women for menopause and low testosterone by giving them estrogen or testosterone, then why do we neglect the other crucial hormones such as Natural thyroid hormone, DHEA (Dehydroepiandrosterone), Melatonin, Human Growth Hormone (HGH)?

We realize the value of natural hormone replacement therapy. In addition to alleviating the symptoms of menopause and reducing risk of osteoporosis, hormone replacement can also aid in the anti-aging process, improve your memory and mood, and create an overall sense of well-being.

We specialize in Bioidentical hormone replacement therapy. After a thorough examination and the necessary lab tests, Our doctor will prescribe for you the proper natural hormones that will have you looking and feeling better than you have in years.

What are bioidentical hormones?

Bioidentical hormones are exactly the same hormones, molecule by molecule that your body produces. They are modified in a lab derived mostly from plant sources but are still considered natural to your body because they are identical. Body does not consider then a foreign substance and so does not cause any adverse reactions.

Synthetic hormones are also made in a lab, but most importantly are not identical to your body. Bioidentical hormones are superior to types of synthetic hormones commonly prescribed.

Testosterone Treatment for Men and Women

Both Men and Women need testosterone for optimal health. Testosterone is needed for libido, muscle strength, leanness, and sense of well-being, cognitive function and mood.

Menopausal women have low to non-detectable testosterone levels with resultant loss of libido and increase in body fat. Return of libido and improved mood return within days of testosterone replacement by transdermal cream. Regrowth of muscle and bone occurs within months and is facilitated by a weight resistance training program.

The testosterone level in males peaks at age 17 and declines 1% per year thereafter. A middle-aged male can therefore have a testosterone level 40% below his peak in young adulthood. This problem can be compounded by the increased production of sex binding globulins, which make the lowered testosterone that is present even less effective. Loss of testosterone in males leads to atherosclerosis and heart attacks, obesity, fatigue, depression, and anxiety. These symptoms come on long before the male loses his sex drive or becomes impotent. There is no evidence that testosterone replacement therapy in males causes prostate cancer or prostate enlargement. In fact, some Urologist-Oncologists say that testosterone may decrease the incidence of prostatic hypertrophy and prostate cancer. Our doctors use topical testosterone replacement as an essential part of its Hormone Replacement Therapy (HRT) program for both men and women based on the patient's total and free testosterone levels and their levels of sex binding globulins.

Boosts male and female libido

Facilitates a healthy heart

Helps prevent osteoporosis

Reduces total body fat

Increases muscle strength, lean body mass

Improves skin and body appearance


Testosterone References:

Carter HB, Pearson JD, Metter EJ, Chan DW, Andres R, Fozard JL, Rosner W, Walsh PC. Prostate 1995 Jul;27(1):25-31.
Longitudinal evaluation of serum androgen levels in men with and without prostate cancer.

There was no correlation of serum testosterone or free testosterone with prostate cancer

Cooper CS, MacIndoe JH, Perry PJ, Yates WR, Williams RD. J Urol 1996 Aug;156(2 Pt 1):438-41; discussion 441-2
The effect of exogenous testosterone on total and free prostate specific antigen levels in healthy young men.

There was no increase in PSA when supplemental testosterone was use.

Estrogen/Progesterone Balancing for Women

Estrogen is an essential sex hormone that declines abruptly in women during their menopause. When women do not initiate a prompt estrogen replacement program at the time of menopause, they undergo accelerated aging manifested by: osteoporosis, senility, heart disease, loss of muscle mass, loss of skin elasticity and thickness, atrophy of the female genitalia, and depression.

Estrogen replacement therapy significantly delays or prevents this accelerated aging process seen in women following menopause. In fact, women who take estrogen replacement have half the degenerative diseases of women who do not take estrogen replacement and live an average of 3.5 years longer. What is even more amazing is that these positive statistics are with those patients on Premarin (non-human estrogen taken from the urine of pregnant horses). The doctors at Physical Medicine Center use only natural estrogen replacement in the form of topical creams; measure estradiol levels and adjusts dosages to pre-menopausal levels. We have every reason to believe that the anti-aging effects of natural human estrogen will be even better than with horse estrogen.

Relives menopausal symptoms

Increases female life expectancy

Protects against coronary artery disease

Boosts brain function

Helps prevent osteoporosis

Protects against Alzheimer's disease

Improves skin and muscle quality

Progesterone is also a female sex hormone that keeps estrogen in balance and is therefore absolutely necessary in the female hormone replacement program regardless of whether the female has a uterus or not.

This concept is not understood by some physicians and this has led to an increase in cancers of the uterus and breast in women on estrogen replacement, alone. Progesterone has powerful anti-cancer properties. In addition, Progesterone facilitates the action of other hormones such as thyroid, testosterone, and endorphins. Synthetic progesterone’s (progestin’s) such as Provera lack many of the beneficial properties of Progesterone and in fact actually serve to increase LDL "the bad form of cholesterol". Provera also does not have the beneficial effect that Progesterone has in increasing bone mass, reversing osteoporosis, and burning fat. Physical Medicine Center orders natural progesterone replacement in our female HRT program as indicated by the individual's blood levels.

Natural antidepressant and tranquilizer

Improves female libido

Protects against cancer

Boosts thyroid action

Helps the body use fat rather than store it

Helps prevent osteoporosis

Optimizing Fertility in Men and Women

Bio-identical (identical as human) hormone replacement therapy, by restoring natural hormone balance, will greatly improve the probability of having a healthy pregnancy. In some cases, a woman may prevent the necessity of treatment at a fertility clinic. There are published reports in the literature with previously infertile women that, after natural hormone replacement, can proceed with normal pregnancies.

Progesterone Treatment for Men

Progesterone is produced by the adrenal glands with levels declining in men throughout their lives. Men become symptomatic and notice fat building up in his breasts and difficulty with urination related to his prostate. Progesterone works by reducing levels of estradiol and DHT, which helps control these problems in men. Additionally, progesterone helps keep the production of aldosterone, cortisol and androgens in balance. Also, progesterone stimulates sperm motility and as such is an aid in male fertility.

Thyroid Balancing and Replacement Therapy

Thyroid hormone is essential for life. Proper thyroid levels are needed for optimal functioning. Conventional medicine replaces thyroid only when indirect laboratory measurements indicate that it is low. At CHI, we perform more elaborate thyroid testing including measuring the free thyroid hormone, which is the active hormone available to the cells in our body. In addition, we also carefully measure the basal body temperature which is the ultimate indicator of whether we are hyper- or hypothyroid. Many times, replacement of human growth hormone or testosterone to more youthful levels creates a greater need for thyroid hormone. In these cases, we add thyroid hormone replacement to our regimen.

Controls cell growth and metabolism

Helps with weight maintenance

Improves heart and vascular health

Renews energy

Improves concentration

Regulates body temperature

Weight Management Treatment


You’ve counted calories and followed the latest diet fads and exercise routines but the pounds just won’t melt away, at least not for long. What are you doing wrong? There are many complex factors that can lie behind weight gain. Our approach to weight management involves a integrated, scientific approach to the problem. The team at Physical Medicine Center takes a multifaceted approach to the problem of weight loss. Since weight gain results from complex relationships between the body’s systems and the environment, no single eating program or weight loss method can work for everyone. One size simply does not fit all. One has to examine carefully all of the potential underlying issues that can influence a person’s weight and then develop an individually tailored approach that corrects the imbalances that lead to weight gain. The goal is long-term health, which can be achieved by correcting imbalances, and a healthy eating and exercise plan.
Dr. Lupo and his team address the following issues that can lead to weight management problems:


  • Stress Hormone Imbalances
  • Food Allergies
  • Female Hormone Imbalances
  • Male Hormone Imbalances
  • Pregnenolone imbalance
  • Insulin Resistance
  • Thyroid Hormone Dysfunction
  • Nutritional Factors
  • Chronic Inflammation
  • Gastrointestinal Imbalances
  • Sleep Deprivation
  • Toxicity (Immune, Neurological, Endocrine)
  • Neurotransmitter Dysfunction
  • Food Addictions
  • Nutritional Factors
What Can You Do?

Contact our office at 813-978-0020 to schedule an initial consultation with our Doctor to determine if you are a candidate for care. After carefully studying your case history and exam findings, he will sit down and explain his recommended plan of action for you. After answering any questions you may have about the recommended plan, you may begin your care with our treatment plan.